Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Ashland NATROSOL 250HX PHARM Hydroxyethylcellulose

Ashland NATROSOL 250HX PHARM is a high-viscosity, pharmaceutical-grade hydroxyethylcellulose (HEC) polymer. Designed for sterile and non-sterile parenteral, ophthalmic, and topical formulations, it offers excellent rheology control, clarity, and thermal stability. Complies with USP/NF, EP, and JP monographs. Batch-certified for pharma use with strict impurity limits and low endotoxin levels. Ideal for viscosity enhancement, suspension stabilization, and controlled release.
  • ashland natrosol 250hx pharm hydroxyethylcellulose_1f500012
  • ashland natrosol 250hx pharm hydroxyethylcellulose_1f500012

Features Of Ashland NATROSOL 250HX PHARM Hydroxyethylcellulose

  1. Pharmaceutical-grade hydroxyethylcellulose (HEC) compliant with USP/NF, EP, and JP monographs.

  2. Highly consistent rheology and viscosity performance across batches, ensuring robust process control in sterile manufacturing.

  3. Excellent cold-water solubility with rapid hydration and minimal claying or fisheyes.

  4. Non-ionic, non-toxic, and non-irritating—suitable for ophthalmic, oral, and topical dosage forms.

  5. Stable across a broad pH range (3–11) and compatible with common preservatives, electrolytes, and active pharmaceutical ingredients (APIs).

Typical Applications Of Ashland NATROSOL 250HX PHARM Hydroxyethylcellulose

  1. Ophthalmic solutions and suspensions (e.g., artificial tears, anti-inflammatory eye drops).

  2. Oral liquid formulations including syrups, suspensions, and elixirs requiring viscosity control and suspension stability.

  3. Topical gels and creams for dermatological and transdermal delivery systems.

  4. Controlled-release matrix tablets and mucoadhesive buccal films.

Specifications Of Ashland NATROSOL 250HX PHARM Hydroxyethylcellulose

Chemical TypeHydroxyethylcellulose (HEC), non-ionic cellulose ether
Product FormWhite to off-white free-flowing powder
AppearanceFree-flowing, odorless, fine granular powder
Primary ApplicationsPharmaceutical liquid and semi-solid dosage forms
Key FeaturesUSP/NF, EP, and JP compliant; low microbial bioburden; low endotoxin
Viscosity (2% aqueous solution, 20°C)200–300 mPa·s (Brookfield RV, spindle #2, 20 rpm)
pH (1% aqueous solution)5.5–8.0
Loss on Drying (105°C, 2 hrs)≤8.0%


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