Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Eastman TBAA tert-Butyl Acetoacetate

Eastman TBAA tert-Butyl Acetoacetate is a high-purity β-ketoester from Eastman’s specialty chemical portfolio. It serves as a versatile building block in pharmaceutical synthesis, agrochemical intermediates, and advanced coatings. Featuring excellent stability and reactivity, TBAA enables efficient alkylation, condensation, and heterocycle formation. Supplied under strict quality control, it supports scalable, reproducible processes across R&D and manufacturing.
  • eastman tbaa tert butyl acetoacetate_e4787373
  • eastman tbaa tert butyl acetoacetate_e4787373

Features Of Eastman TBAA tert-Butyl Acetoacetate

  1. High chemical purity with low residual acid content, ensuring superior stability in sensitive synthetic reactions.

  2. Enhanced steric protection from the tert-butyl group minimizes undesired enolization and side reactions.

  3. Excellent solubility in common organic solvents including toluene, THF, and ethyl acetate, facilitating homogeneous reaction conditions.

  4. Controlled hydrolytic lability—stable under neutral storage conditions but cleanly cleavable under mild acidic or thermal deprotection protocols.

  5. Consistent batch-to-batch performance validated by rigorous GC and NMR quality control.

Typical Applications Of Eastman TBAA tert-Butyl Acetoacetate

  1. Building block for pharmaceutical intermediates, especially in β-keto ester–based heterocycle synthesis (e.g., pyrazoles, isoxazoles).

  2. Key acylating agent in agrochemical active ingredient synthesis requiring regioselective enolate alkylation.

  3. Monomer precursor in specialty polymer design, enabling controlled branching and post-polymerization functionalization.

  4. Protecting-group strategy for acetoacetic acid derivatives in multistep fine chemical synthesis.

  5. Reagent in catalytic asymmetric transformations where steric modulation improves enantioselectivity.

Specifications Of Eastman TBAA tert-Butyl Acetoacetate

Chemical TypeProtected β-keto ester
Product FormLiquid
AppearanceColorless to pale yellow clear liquid
Primary ApplicationsPharmaceutical intermediates, agrochemicals, specialty polymers
Key FeaturesSterically hindered tert-butyl protection, high enolizability control, low acidity
BenefitsImproved reaction selectivity, reduced side-product formation, simplified purification
Storage RecommendationStore under inert atmosphere at 15–25 °C; protect from moisture and strong acids
CAS Number3034-38-6


Get in Touch with ERICW
Let competitive chemical materials go global.

Your Name *

Your Email *

Your Phone

Country

Your Message *