High chemical purity with low residual acid content, ensuring superior stability in sensitive synthetic reactions.
Enhanced steric protection from the tert-butyl group minimizes undesired enolization and side reactions.
Excellent solubility in common organic solvents including toluene, THF, and ethyl acetate, facilitating homogeneous reaction conditions.
Controlled hydrolytic lability—stable under neutral storage conditions but cleanly cleavable under mild acidic or thermal deprotection protocols.
Consistent batch-to-batch performance validated by rigorous GC and NMR quality control.
Building block for pharmaceutical intermediates, especially in β-keto ester–based heterocycle synthesis (e.g., pyrazoles, isoxazoles).
Key acylating agent in agrochemical active ingredient synthesis requiring regioselective enolate alkylation.
Monomer precursor in specialty polymer design, enabling controlled branching and post-polymerization functionalization.
Protecting-group strategy for acetoacetic acid derivatives in multistep fine chemical synthesis.
Reagent in catalytic asymmetric transformations where steric modulation improves enantioselectivity.
| Chemical Type | Protected β-keto ester |
| Product Form | Liquid |
| Appearance | Colorless to pale yellow clear liquid |
| Primary Applications | Pharmaceutical intermediates, agrochemicals, specialty polymers |
| Key Features | Sterically hindered tert-butyl protection, high enolizability control, low acidity |
| Benefits | Improved reaction selectivity, reduced side-product formation, simplified purification |
| Storage Recommendation | Store under inert atmosphere at 15–25 °C; protect from moisture and strong acids |
| CAS Number | 3034-38-6 |
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