Highly uniform particle size distribution for consistent flow and compression behavior.
Optimized crystallinity and surface morphology to enhance tablet tensile strength and disintegration performance.
Low moisture content (<5.0%) ensuring excellent stability during storage and processing.
Free-flowing powder with low dust generation, improving handling safety and operational efficiency.
Pharmaceutical-grade purity compliant with USP/NF, EP, and JP monographs for excipients.
Direct compression tablet formulation in oral solid dosage forms.
Binder and filler in chewable and rapidly disintegrating tablets.
Stabilizer and bulking agent in lyophilized biopharmaceutical formulations.
Excipient in veterinary pharmaceutical tablets and capsules.
Carrier in dry powder inhaler (DPI) formulations requiring high aerosolization efficiency.
| Chemical Type | Microcrystalline cellulose (MCC) |
| Product Form | Free-flowing white powder |
| Appearance | White to off-white, odorless, tasteless powder |
| Primary Applications | Pharmaceutical direct compression, binder, disintegrant, stabilizer |
| Key Features | Controlled particle size, high compressibility, low moisture, low endotoxin |
| Compliance | USP/NF, EP 10.0, JP 17, ISO 9001 certified manufacturing |
| Particle Size (D50) | 100–120 µm (laser diffraction) |
| Loss on Drying (LOD) | ≤4.5% (105°C, 2 h) |
Q1: What is the primary functional role of CEOLUS PH-102 in pharmaceutical solid dosage forms?
A: CEOLUS PH-102 serves primarily as a binder and disintegrant in direct compression tablet formulations, offering excellent compactibility and rapid wetting to support robust tablet formation and consistent dissolution performance.
Q2: How does PH-102 compare to standard microcrystalline cellulose grades in terms of flow and compressibility?
A: PH-102 is engineered for superior powder flow and higher compressibility compared to conventional MCC grades, enabling improved content uniformity and reduced weight variation during high-speed tableting without requiring additional glidants or lubricants in many cases.
Q3: Is CEOLUS PH-102 suitable for use in oral dispersible tablets (ODTs) and other fast-dissolving systems?
A: Yes — its optimized particle morphology and high surface area promote rapid water penetration and structural disintegration, making it well-suited for ODTs and other rapidly dissolving dosage forms where quick dispersion and low residual grittiness are critical.
Q4: What are the recommended storage conditions to maintain PH-102’s performance characteristics?
A: Store in a cool, dry place at controlled room temperature, protected from moisture and direct sunlight. Keep containers tightly sealed to prevent hygroscopic uptake, which may affect flowability and compaction behavior over time.
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E-mail: wangxingqiang@ericwchem.com
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