Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Ashland Benecel A4C Pharm Methylcellulose

Ashland Benecel A4C Pharm Methylcellulose is a high-purity, USP/EP-grade pharmaceutical excipient—part of Ashland’s Benecel™ cellulose ether portfolio—designed for controlled-release tablets, granulation, and viscosity modulation. It offers excellent cold-water solubility, film-forming capability, and batch-to-batch consistency, meeting stringent regulatory requirements for oral solid dosage forms.
  • ashland benecel a4c pharm methylcellulose_e85ada17
  • ashland benecel a4c pharm methylcellulose_e85ada17

Features Of Ashland Benecel A4C Pharm Methylcellulose

  1. Pharmaceutical-grade methylcellulose meeting USP/NF, EP, and JP monograph requirements.

  2. Controlled viscosity profile (400–600 mPa·s in 2% aqueous solution at 20°C) for consistent formulation performance.

  3. Excellent cold-water solubility with rapid dispersion and minimal lump formation.

  4. High purity with low residual methanol and heavy metals—optimized for oral solid dosage forms.

  5. Thermally reversible gelation behavior enabling use in hot-melt extrusion and sustained-release matrix systems.

Typical Applications Of Ashland Benecel A4C Pharm Methylcellulose

  1. Matrix-forming polymer in immediate-release and modified-release tablets.

  2. Viscosity-enhancing agent in liquid and semi-solid oral suspensions and syrups.

  3. Binder in direct compression and wet granulation processes.

  4. Coating component for functional film coatings in tablet and capsule applications.

  5. Stabilizer and thickener in ophthalmic solutions and nasal sprays.

Specifications Of Ashland Benecel A4C Pharm Methylcellulose

Chemical TypeMethylcellulose ether (non-ionic cellulose derivative)
Product FormWhite to off-white free-flowing powder
AppearanceOdorless, tasteless, fine granular powder
Primary ApplicationsOral solid dosage forms, liquid formulations, topical preparations
Key FeaturesUSP/NF, EP, JP compliant; low endotoxin; suitable for GMP manufacturing
BenefitsBatch-to-batch consistency, high reproducibility in compaction and dissolution, regulatory support documentation available
pH of 1% Aqueous Solution5.0–8.0
Loss on Drying≤8.0% (at 105°C for 2 hours)


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