Name: Ashland Benecel A4M Pharm Methylcellulose
Brand: Guangzhou Eric Wei Chemical Co., Ltd.

Features Of Ashland Benecel A4M Pharm Methylcellulose

Pharmaceutical-grade purity compliant with USP/NF, EP, and JP monographs for oral solid dosage forms.
Consistent viscosity performance (4–6 mPa·s in 2% aqueous solution at 20°C) ensuring reliable tablet binder functionality.
Excellent cold-water solubility with rapid hydration and minimal claying, enabling efficient wet granulation processes.
Non-ionic, pH-independent behavior across physiological ranges (pH 3–11), supporting formulation stability in diverse APIs.
Low endotoxin levels (<0.5 EU/mg) and stringent microbial control meeting ICH Q5D and compendial requirements for sterile and non-sterile products.

Typical Applications Of Ashland Benecel A4M Pharm Methylcellulose

Primary binder in direct compression and wet granulation of immediate-release tablets.
Controlled-release matrix former in hydrophilic polymer-based extended-release tablets.
Viscosity enhancer and suspending agent in oral liquid suspensions and syrups.
Protective colloid and film-forming agent in pharmaceutical coating formulations.
Excipient in lyophilized formulations and ophthalmic solutions requiring low osmolality and high clarity.

Chemical Type	Methylcellulose ether (non-ionic cellulose derivative)
Product Form	White to off-white free-flowing powder
Appearance	Fine, odorless, tasteless powder
Viscosity (2% w/w aqueous solution, 20°C)	4–6 mPa·s
Methoxy Substitution (USP/NF)	27.0–30.0%
Loss on Drying (105°C, 2 h)	≤5.0%
Residue on Ignition	≤1.5%
Microbial Limits (USP <61>)	Total aerobic count ≤100 CFU/g; absence of E. coli, Salmonella, and S. aureus

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E-mail: wangxingqiang@ericwchem.com
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