Ashland Benecel HPMC 2208K K4M is a high-quality direct compression (DC) grade hydroxypropyl methylcellulose in the Benecel 2208K series. Custom-designed for direct compression production of oral controlled-release tablets, it meets stringent international pharmacopoeia standards, featuring excellent compressibility and flowability
Excellent DC Adaptation - Designed for direct compression process, with excellent flowability and compressibility, simplifying production workflow
Precise Controlled-Release Regulation - Forms gel matrix structure, stably regulating drug release for long-acting administration
Efficient Binding & Molding - Excellent binding performance, ensuring uniform tablet hardness and reducing friability risk
Broad Process Compatibility - Suitable for diverse drug formulations, highly compatible with common excipients, flexible in application
Controlled-Release Tablet Preparation - Used for direct compression of oral sustained-release and controlled-release tablets to construct gel matrix system
Compound Formulation Production - Used in preparation of multi-component compound tablets to ensure component uniformity and release stability
Low-Dose Drug Molding - Used for direct compression of low-dose drug tablets to improve content uniformity and production efficiency
Modified Formulation R&D - Used in drug formulation modification to optimize release profile and patient compliance
| Brand | Ashland (USA) |
| Chemical Type | Hydroxypropyl Methylcellulose (HPMC) Type 2208, non-ionic cellulose ether |
| Physical Form | White to off-white free-flowing powder |
| Core Characteristics | DC adaptation, precise controlled-release, efficient binding |
| CAS Number | 9004-65-3 |
| Weight-Average Molecular Weight | 400,000 |
| Viscosity (2% aqueous solution) | 2700 - 5040 mPa·s |
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