Ashland Benecel HPMC 2208K K100M is a high-quality high-viscosity water-soluble polymer of hydroxypropyl methylcellulose in the Benecel 2208K series. Custom-designed for controlled-release matrices of oral solid dosage forms, direct compression and multi-layer tablet preparation, it meets stringent international pharmacopoeia standards
Efficient Controlled-Release Matrix - High-viscosity hydrophilic gel feature, precisely regulating drug release rate for long-acting stable administration
Excellent Tableting Adaptation - Optimized particle distribution and bulk density, suitable for high-speed tableting, ensuring tablet weight uniformity
Strong Interlayer Bonding - Superior interfacial bonding strength, enhancing multi-layer tablet stability and reducing delamination risk
Low Nitrite Advantage - Nitrite content <200ppb, reducing nitrosamine formation risk and improving formulation safety
Controlled-Release Matrix Formulations - Used as hydrophilic matrix material to prepare long-acting controlled-release tablets and granules
Direct Compression Production - Used for direct compression of various oral tablets to improve production efficiency and product stability
Multi-Layer Tablet Preparation - Used for multi-layer controlled-release tablets to ensure interlayer bonding strength and overall stability
Wet Granulation Process - Used as binder in tablet wet granulation to improve particle formability and flowability
| Chemical Type | Hydroxypropyl Methylcellulose (HPMC) Type 2208,non-ionic cellulose ether |
| Physical Form | White to off-white free-flowing powder |
| Core Characteristics | High viscosity,Water-soluble,Controlled-release matrix,High-speed tableting adaptation |
| CAS Number | 9004-65-3 |
| Viscosity (mPa·s) | 75,000-140,000(2% aqueous solution, 20℃) |
| Degree of Substitution | Methoxyl content 19.0-24.0%,Hydroxypropoxyl content 4.0-12.0% |
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