Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Ashland Benecel HPMC 2208K K100M Hydroxyethyl Cellulose

Ashland Benecel HPMC 2208K K100M is a high-quality high-viscosity water-soluble polymer of hydroxypropyl methylcellulose in the Benecel 2208K series. Custom-designed for controlled-release matrices of oral solid dosage forms, direct compression and multi-layer tablet preparation, it meets stringent international pharmacopoeia standards

Features Of Ashland Benecel HPMC 2208K K100M Hydroxyethyl Cellulose

  1. Efficient Controlled-Release Matrix - High-viscosity hydrophilic gel feature, precisely regulating drug release rate for long-acting stable administration

  2. Excellent Tableting Adaptation - Optimized particle distribution and bulk density, suitable for high-speed tableting, ensuring tablet weight uniformity

  3. Strong Interlayer Bonding - Superior interfacial bonding strength, enhancing multi-layer tablet stability and reducing delamination risk

  4. Low Nitrite Advantage - Nitrite content <200ppb, reducing nitrosamine formation risk and improving formulation safety

Typical Applications Of Ashland Benecel HPMC 2208K K100M Hydroxyethyl Cellulose

  1. Controlled-Release Matrix Formulations - Used as hydrophilic matrix material to prepare long-acting controlled-release tablets and granules

  2. Direct Compression Production - Used for direct compression of various oral tablets to improve production efficiency and product stability

  3. Multi-Layer Tablet Preparation - Used for multi-layer controlled-release tablets to ensure interlayer bonding strength and overall stability

  4. Wet Granulation Process - Used as binder in tablet wet granulation to improve particle formability and flowability

Specifications Of Ashland Benecel HPMC 2208K K100M Hydroxyethyl Cellulose

Chemical TypeHydroxypropyl Methylcellulose (HPMC) Type 2208,non-ionic cellulose ether
Physical FormWhite to off-white free-flowing powder
Core CharacteristicsHigh viscosity,Water-soluble,Controlled-release matrix,High-speed tableting adaptation
CAS Number9004-65-3
Viscosity (mPa·s)75,000-140,000(2% aqueous solution, 20℃)
Degree of SubstitutionMethoxyl content 19.0-24.0%,Hydroxypropoxyl content 4.0-12.0%


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