Ashland Klucel HPC MF is a high-quality medium-molecular-weight hydroxypropyl cellulose polymer in the Klucel series. Custom-designed for binding granulation, film coating of oral solid dosage forms and hydrophobic drug formulations, it meets stringent international pharmacopoeia standards, featuring water-oil dual solubility
Water-Oil Dual Solubility Adaptation - Soluble in both water and organic solvents, flexibly adapting to diverse formulation systems
Flexible Film-Forming Protection - Forms tough, crack-resistant films without additional plasticizers, enhancing coating protection
Efficient Binding & Molding - Excellent binding performance, suitable for hydrophobic drug granulation, ensuring uniform and stable particles
Low Surface Tension Enhancement - Low solution surface tension improves wetting effect of hydrophobic drugs, optimizing granulation quality
Hydrophobic Drug Granulation - Used as binder in wet granulation of hydrophobic drugs to improve particle molding quality
Formulation Binding & Granulation - Used as binder in tablet wet granulation and dry granulation to ensure particle flowability
Pharmaceutical Film Coating - Used for film coating of oral tablets to enhance flexibility and stability of coating layers
Direct Compression Production - Used for direct compression of oral tablets to simplify processes and improve production efficiency
| Chemical Type | Hydroxypropyl Cellulose (HPC), non-ionic cellulose ether |
| Physical Form | White to off-white free-flowing powder |
| Core Characteristics | Medium molecular weight, water-oil dual solubility, flexible film formation, efficient binding |
| CAS Number | 9004-64-2 |
| Weight-Average Molecular Weight | 200,000 |
| Viscosity (5% aqueous solution, Brookfield) | 400 - 1000 mPa·s |
| Pharmacopoeia Standard | Complies with United States Pharmacopeia (USP), European Pharmacopoeia (EP), |
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