Ashland Benecel HPMC 2208K K35M is a high-quality mid-to-high viscosity water-soluble polymer of hydroxypropyl methylcellulose in the Benecel 2208K series. Custom-designed for sustained-release matrices of oral solid dosage forms, direct compression and wet granulation, it meets stringent international pharmacopoeia standards
Precise Sustained-Release Regulation - Mid-to-high viscosity hydrophilic gel feature, stably regulating drug release rate for long-acting administration
Efficient Tableting Adaptation - Optimized particle morphology and bulk density, suitable for high-speed tableting, ensuring tablet weight uniformity
Strong Binding & Molding - Excellent binding performance, enhancing tablet hardness and molding stability, reducing friability risk
Multi-National Pharmacopoeia Compliance - Meets USP/EP/JP standards, high-purity pharm-grade quality, excellent batch stability
Direct Compression Production - Used for direct compression of various oral tablets to simplify processes and improve production efficiency
Wet Granulation Process - Used as binder in tablet wet granulation to improve particle formability and flowability
Multi-Layer Tablet Preparation - Used for multi-layer sustained-release tablets to ensure interlayer bonding strength and overall stability
Pharmaceutical Film Coating - Used as formulation film coating material to optimize appearance protection and storage stability
| Chemical Type | Hydroxypropyl Methylcellulose (HPMC) Type 2208,non-ionic cellulose ether |
| Physical Form | White to off-white free-flowing powder |
| Core Characteristics | Mid-to-high viscosity,Water-soluble,Sustained-release matrix,High compressibility |
| CAS Number | 9004-65-3 |
| Weight-Average Molecular Weight | 675,000 |
| Viscosity (mPa·s) | 26,250-49,000(2% aqueous solution, 20℃) |
| Degree of Substitution | Methoxyl content 19.0-24.0%,Hydroxypropoxyl content 4.0-12.0% |
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