Features Of Ashland Aqualon EC-N50 PHARM Ethyl Cellulose
Pharmaceutical-Grade High Purity & Compliance - Meets USP, BP, PhEur and other pharmacopoeia standards, ignition residue ≤0.4%, heavy metals ≤20ppm, suitable for oral and external dosage forms.
Powerful Film-Forming & Sustained-Release - Uniform and tough film-forming, water-insoluble suitable for membrane-controlled sustained-release, precisely regulating drug release rate.
Chemical Stability & Weather Resistance - Resistant to acid, alkali and ion interference, light and heat stable, suitable for complex systems, stable performance during long-term storage.
Wide Solvent Compatibility - Easily soluble in chloroform, THF, aromatic hydrocarbons and other organic solvents, suitable for multi-process formulation systems.
Typical Applications Of Ashland Aqualon EC-N50 PHARM Ethyl Cellulose
Pharmaceutical Solid Preparations - Used as membrane-controlled sustained-release coating and matrix material for tablets/pellets, masking taste and moisture-proof, improving storage stability.
Fine Chemical Microcapsules - Used for microencapsulation of active ingredients, controlling release, improving ingredient stability and bioavailability.
Cosmetic Film-Forming & Setting - Used in mascara, eyeliner, etc., film-forming and setting, waterproof and sweat-proof, improving makeup durability.
Electronic Paste Bonding - Used as binder for electronic pastes, improving paste adhesion and film compactness, ensuring electrical conductivity.
Specifications Of Ashland Aqualon EC-N50 PHARM Ethyl Cellulose
| Chemical Name | Ethylcellulose (EC) |
| CAS No. | 9004-57-3 |
| Appearance | Off-white or beige odorless fine particle/powder |
| Ethoxy Content | 48.0-49.5% |
| Dynamic Viscosity (25°C) | 40-52 mPa·s |
| Molecular Weight | Approx. 160,000 |
| Ignition Residue | ≤0.4% |
| Heavy Metals | ≤20 ppm |
Ashland Aqualon EC-N50 PHARM Ethyl Cellulose – Frequently Asked Questions (FAQ)
Q1: What is the primary pharmaceutical application of EC-N50 PHARM?
A: EC-N50 PHARM is primarily used as a functional film-coating agent and controlled-release matrix former in oral solid dosage forms, including immediate- and extended-release tablets and pellets.
Q2: How does EC-N50 PHARM differ from standard ethyl cellulose grades?
A: EC-N50 PHARM is specifically purified and manufactured under pharmaceutical-grade conditions to meet stringent quality, purity, and consistency requirements for use in human drug products — including tighter control over residual solvents, heavy metals, and microbial limits.
Q3: Is EC-N50 PHARM suitable for hot-melt extrusion (HME) applications?
A: Yes, EC-N50 PHARM is commonly selected for HME-based formulations due to its thermal stability, low melt viscosity, and compatibility with active pharmaceutical ingredients and plasticizers like triethyl citrate.
Q4: What solvent systems are typically used to dissolve EC-N50 PHARM for coating or extrusion?
A: It is readily soluble in common organic solvent blends such as ethanol/water, isopropanol/water, and acetone/ethanol; aqueous dispersions (e.g., Aquacoat® ECD) are also widely used to avoid flammable solvents during manufacturing.
Q5: How should EC-N50 PHARM be stored to maintain its performance characteristics?
A: Store in original unopened packaging at room temperature in a dry, well-ventilated area, protected from moisture and direct sunlight; once opened, reseal tightly and use within a reasonable timeframe to prevent hygroscopic uptake.
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