Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Asahi Kasei RC-A591NF Microcrystalline Cellulose-Sodium Carboxymethyl Cellulose

AsahiKaseiRC-A591NFMicrocrystallineCellulose-SodiumCarboxymethylCelluloseisahigh-performancepharmaceuticalexcipientcombiningMCC’sexcellentcompressibilitywithCMC-Na’ssuperiorbindinganddisintegrationproperties.Idealfordirectcompressiontablets,itoffersenhancedflow,uniformdensity,andrapiddissolutionwithoutcompromisingstabilityorcompatibility.
  • asahi kasei rc a591nf microcrystalline cellulose sodium carboxymethyl cellulose_73918b54
  • asahi kasei rc a591nf microcrystalline cellulose sodium carboxymethyl cellulose_73918b54

Features Of Asahi Kasei RC-A591NF Microcrystalline Cellulose-Sodium Carboxymethyl Cellulose

  1. Optimized dual-polymer synergy: Combines the compressibility and flowability of microcrystalline cellulose (MCC) with the superior binder functionality and wet granulation performance of sodium carboxymethyl cellulose (Na-CMC).

  2. Free-flowing, low-dust powder formulation designed for high-speed direct compression and roller compaction processes.

  3. Consistent particle size distribution and excellent batch-to-batch reproducibility, supporting robust pharmaceutical manufacturing.

  4. Non-ionic and pH-stable across typical formulation ranges (pH 3–8), minimizing compatibility risks with acid- or base-sensitive APIs.

  5. Complies with major pharmacopoeial standards including USP-NF, EP, and JP for excipients used in oral solid dosage forms.

Typical Applications Of Asahi Kasei RC-A591NF Microcrystalline Cellulose-Sodium Carboxymethyl Cellulose

  1. Direct compression tablets requiring enhanced tablet strength and rapid disintegration.

  2. High-drug-load formulations where improved binder efficiency and content uniformity are critical.

  3. Immediate-release oral solid dosage forms, including film-coated and uncoated tablets.

  4. Wet granulation processes leveraging Na-CMC’s superior binding without requiring additional binders.

  5. Pharmaceutical applications demanding regulatory-ready, well-characterized cellulose-based excipients.

Specifications Of Asahi Kasei RC-A591NF Microcrystalline Cellulose-Sodium Carboxymethyl Cellulose

Chemical TypeCo-processed excipient: Microcrystalline Cellulose (MCC) / Sodium Carboxymethyl Cellulose (Na-CMC)
Product FormFree-flowing white to off-white powder
AppearanceHomogeneous, fine particulate powder with no visible grit or lumps
Primary ApplicationsOral solid dosage forms — direct compression, wet granulation, roller compaction
Key FeaturesDual-functionality binder-filler; low moisture content; non-ionic; non-reducing
BenefitsImproved tablet hardness, reduced friability, faster disintegration vs. standard MCC alone
Regulatory StatusComplies with USP-NF, Ph. Eur., and JP monographs for MCC and Na-CMC
Storage ConditionsStore in original sealed container at 15–25°C, relative humidity <60%


Get in Touch with ERICW
Let competitive chemical materials go global.

Your Name *

Your Email *

Your Phone

Country

Your Message *