Tri-block copolymer structure (PEO–PPO–PEO) enabling excellent temperature-responsive micellization behavior.
High molecular weight (~14,600 g/mol) providing superior steric stabilization in colloidal and nanoparticle systems.
Non-ionic, low toxicity profile compliant with ICH Q3C guidelines for pharmaceutical excipient use.
Outstanding solubilizing capacity for hydrophobic actives, including poorly water-soluble APIs and fragrances.
Good thermal and pH stability across broad processing conditions (pH 3–11, up to 60 °C).
Stabilizer in injectable nanomedicine formulations (e.g., polymeric micelles, liposomes, and protein therapeutics).
Emulsifier and viscosity modifier in high-end personal care emulsions and cleansing gels.
Dispersing agent for ceramic slurries and advanced battery electrode coatings.
Solubilizer and crystallization inhibitor in pharmaceutical solid dispersion and amorphous formulation development.
Surface modifier for biomedical device coatings requiring non-fouling and biocompatible interfaces.
| Chemical Type | Non-ionic triblock copolymer (poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)) |
| Product Form | White to off-white flake or powder |
| Appearance | Free-flowing, hygroscopic solid |
| Primary Applications | Pharmaceutical excipient, nanocarrier stabilizer, emulsion stabilizer, solubilizer |
| Key Features | Thermo-responsive micelle formation, low CMC (~0.005 wt%), high HLB (~22) |
| Benefits | Enhanced drug loading, improved formulation stability, reduced interfacial tension, GRAS-eligible for select applications |
| Regulatory Status | Complies with USP/NF, Ph. Eur., and JP monographs for Poloxamer 188 analogues; listed in FDA Inactive Ingredients Guide (IV route) |
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