Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Solvay Antarox F 127 NF Polyoxyethylene-Polyoxypropylene Block Copolymer Nonionic Surfactant

Solvay Antarox F 127 NF is a nonionic surfactant featuring polyoxyethylene-polyoxypropylene block copolymer chemistry. Designed for pharmaceutical and food-grade applications, it offers excellent wetting, solubilization, and emulsification performance with low foaming and high biocompatibility. Compliant with USP/NF and EP standards, it ensures regulatory readiness and batch-to-batch consistency in sensitive formulations.
  • solvay antarox f 127 nf polyoxyethylene polyoxypropylene block copolymer nonioni_6a246e71
  • solvay antarox f 127 nf polyoxyethylene polyoxypropylene block copolymer nonioni_6a246e71

Features Of Solvay Antarox F 127 NF Polyoxyethylene-Polyoxypropylene Block Copolymer Nonionic Surfactant

  1. Highly effective nonionic surfactant with balanced hydrophilic-lipophilic properties for broad compatibility in aqueous and semi-aqueous systems.

  2. Excellent wetting, emulsifying, and solubilizing performance across a wide pH range (pH 3–11), without sensitivity to electrolytes.

  3. Complies with U.S. FDA 21 CFR §172.828 and EU Regulation (EC) No 178/2002 for food-contact indirect applications (NF grade).

  4. Low foaming profile suitable for high-shear and recirculating cleaning processes in industrial and pharmaceutical settings.

  5. Thermally stable up to 80 °C and compatible with common excipients, APIs, and formulation matrices.

Typical Applications Of Solvay Antarox F 127 NF Polyoxyethylene-Polyoxypropylene Block Copolymer Nonionic Surfactant

  1. Pharmaceutical tablet coatings and film-forming agents in oral solid dosage forms.

  2. Stabilizer in parenteral emulsions and liposomal drug delivery systems.

  3. Cleaning agent in CIP (Clean-in-Place) formulations for biopharmaceutical manufacturing equipment.

  4. Wetting and dispersing aid in agrochemical suspension concentrates (SC) and water-dispersible granules (WDG).

  5. Emulsifier in personal care emulsions requiring mildness and low irritation potential.

Specifications Of Solvay Antarox F 127 NF Polyoxyethylene-Polyoxypropylene Block Copolymer Nonionic Surfactant

Chemical TypePolyoxyethylene-polyoxypropylene block copolymer (Pluronic®-type)
Product FormOff-white to pale yellow flake or granular solid
AppearanceFree-flowing, non-hygroscopic solid at room temperature
HLB Value~12.0 (calculated)
SolubilityFreely soluble in water; soluble in ethanol, propylene glycol, and glycerin
pH (1% aqueous solution)5.5–7.0
Heavy Metals (as Pb)<10 ppm
Microbial Limits (NF Grade)Complies with USP <61>: Total aerobic count ≤100 CFU/g; absence of E. coli, Salmonella, and Staphylococcus aureus


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