Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Wacker HDK N20 Pharma Fumed Silica

Wacker HDK® N20 Pharma is a high-purity fumed silica designed for pharmaceutical applications. It serves as a versatile flow aid, anti-caking agent, and rheology modifier in solid dosage forms. Produced under strict GMP conditions, it meets USP<1380>, EP 2.5.14, and ISO 9001 standards. Its ultrafine particle size (≈7 nm) and specific surface area (~200 m²/g) ensure exceptional performance in tablet formulations and inhalation powders.
  • wacker hdk n20 pharma fumed silica_c4aa2fbe
  • wacker hdk n20 pharma fumed silica_c4aa2fbe

Features Of Wacker HDK N20 Pharma Fumed Silica

  1. Pharmaceutical-grade purity compliant with USP <857>, EP 2.10, and JP XVII standards.

  2. Highly consistent particle size distribution (primary particle size: ~20 nm) ensuring reproducible rheology control.

  3. Low residual sulfate and heavy metal content, meeting stringent ICH Q3D elemental impurity requirements.

  4. Free-flowing, non-agglomerated fumed silica powder optimized for gentle incorporation into dry blends.

  5. Batch-to-batch consistency certified via comprehensive QC testing including BET surface area, DBP absorption, and pH.

Typical Applications Of Wacker HDK N20 Pharma Fumed Silica

  1. Anti-caking agent in direct compression tablet formulations.

  2. Rheology modifier in liquid oral suspensions and topical gels.

  3. Flow aid for low-dose active pharmaceutical ingredients (APIs) in high-potency solid dosage forms.

  4. Stabilizer in sterile parenteral suspensions and lyophilized formulations.

  5. Processing aid in inhalation powder formulations to improve aerosol dispersion efficiency.

Specifications Of Wacker HDK N20 Pharma Fumed Silica

Chemical TypeSynthetic amorphous silicon dioxide (SiO₂)
Product FormFree-flowing white powder
AppearanceWhite, odorless, fine particulate powder
BET Surface Area190–210 m²/g
DBP Absorption150–170 mL/100 g
pH (4% aqueous suspension)3.6–4.2
Loss on Drying (105 °C, 2 h)≤1.5%
Sulfate (SO₄²⁻)≤50 ppm


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