Ultra-low residual amine content to minimize side reactions during solid-phase peptide synthesis (SPPS).
Rigorously controlled acidity (pH 6.5–7.5 in aqueous solution) for optimal coupling efficiency and resin stability.
High purity (>99.9% GC assay) with stringent limits on aldehydes, water, and heavy metals per peptide-grade specifications.
Batch-to-batch consistency certified via comprehensive QC testing including NMR, GC-MS, and titration.
Supplied in inert, moisture-barrier packaging to preserve neutralizing capacity and prevent DMF decomposition.
Solid-phase peptide synthesis (SPPS) as a high-fidelity solvent and neutralizing agent for Fmoc deprotection steps.
Preparation of cGMP-compliant peptide APIs where trace impurity control is critical for regulatory filing.
Use in automated peptide synthesizers requiring consistent solvation power and minimal base-catalyzed racemization.
Research-scale synthesis of complex cyclic and glycopeptides demanding ultra-pure, non-nucleophilic reaction media.
| Chemical Type | Dimethylformamide (DMF) – Neutralized Peptide Grade |
| Product Form | Liquid |
| Appearance | Clear, colorless liquid |
| pH (10% w/w aqueous solution) | 6.5 – 7.5 |
| Water Content (KF) | ≤ 50 ppm |
| Residual Amines (as dimethylamine) | ≤ 10 ppm |
| Aldehyde Content (as formaldehyde) | ≤ 5 ppm |
| Heavy Metals (as Pb) | ≤ 1 ppm |
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