Pharmaceutical-grade ethyl cellulose meeting USP/NF, EP, and JP monograph requirements.
Consistent batch-to-batch performance with tight control over ethoxy substitution (48.0–49.5%) and viscosity (6–9 mPa·s in 5% toluene/ethanol 80/20).
Free-flowing, off-white to light tan granular powder with low moisture content (<5.0%).
Non-ionic, thermoplastic polymer offering excellent film-forming capability and sustained-release functionality.
Compatible with common pharmaceutical excipients and suitable for hot-melt extrusion and fluid-bed coating processes.
Sustained-release matrix tablets and multiparticulate systems (e.g., pellets, granules).
Functional film coatings for taste masking, moisture barrier, and controlled drug release.
Binders and rheology modifiers in liquid and semi-solid formulations.
Stabilizer in topical suspensions and emulsions requiring non-ionic, water-insoluble polymers.
Carrier material in hot-melt extruded solid dispersions for poorly soluble APIs.
| Chemical Type | Ethyl cellulose ether derivative |
| Product Form | Free-flowing granular powder |
| Appearance | Off-white to light tan, odorless granules |
| Primary Applications | Oral sustained-release dosage forms, functional film coatings |
| Key Features | USP/NF, EP, JP compliant; low viscosity grade; thermoplastic |
| Benefits | Robust film integrity, predictable release kinetics, processing versatility |
| Storage Conditions | Store in original sealed container at 15–30°C, protected from moisture |
| Shelf Life | 36 months from date of manufacture when stored properly |
Q1: What is the primary functional role of Ashland Aqualon N7 Pharm Ethyl Cellulose in pharmaceutical formulations?
A: Ashland Aqualon N7 Pharm Ethyl Cellulose is primarily used as a film-forming agent, binder, and sustained-release matrix former in oral solid dosage forms such as tablets and pellets. Its water-insoluble nature enables controlled drug release profiles while maintaining mechanical integrity during processing and storage.
Q2: Is Ashland Aqualon N7 Pharm Ethyl Cellulose suitable for use in immediate-release tablet coatings?
A: While it is not typically selected for standard immediate-release aqueous film coatings due to its water insolubility, it can be incorporated into specialized functional coatings—such as moisture barriers or taste-masking layers—when blended with other polymers or applied via organic solvent-based systems.
Q3: How does the viscosity grade 'N7' relate to processing behavior in wet granulation or extrusion-spheronization?
A: The 'N7' designation indicates a medium-viscosity grade, offering balanced solution rheology and powder flow characteristics. It generally provides sufficient binding strength in wet granulation without excessive viscosity build-up, and supports consistent extrudate formation in spheronization processes when used at typical concentrations.
Q4: Can this grade be processed using common pharmaceutical manufacturing equipment without special modifications?
A: Yes—Ashland Aqualon N7 Pharm Ethyl Cellulose is compatible with standard high-shear mixers, fluid bed dryers, extruders, and spheronizers. It dissolves readily in common organic solvents (e.g., ethanol, isopropanol, acetone) and can be handled safely under typical GMP conditions without requiring dedicated equipment upgrades.
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