Enteric polymer that dissolves only at pH ≥ 5.5, enabling targeted intestinal drug release.
Excellent film-forming capability for robust enteric coating of oral solid dosage forms.
Good solubility in common organic solvents (e.g., acetone, ethanol, isopropanol) and water-miscible co-solvent systems.
Thermally stable with low moisture sensitivity, supporting consistent processing during fluid-bed or pan coating.
Complies with major pharmacopoeial standards including USP/NF and EP monographs for HPMCAS.
Enteric coating for tablets and capsules to prevent gastric degradation of acid-labile APIs.
Amorphous solid dispersion (ASD) carrier to enhance solubility and bioavailability of poorly water-soluble drugs.
Stabilizer and matrix former in hot-melt extrusion (HME) formulations.
Functional excipient in controlled-release multiparticulate systems (e.g., pellets, granules).
Coating agent for functional food and nutraceutical delivery systems requiring pH-triggered release.
| Chemical Type | Hydroxypropyl methylcellulose acetate succinate (HPMCAS) |
| Product Form | Free-flowing white to off-white powder |
| Appearance | White to light tan, odorless, free-flowing powder |
| Primary Applications | Enteric coating, amorphous solid dispersions, controlled-release formulations |
| Key Features | pH-dependent solubility, film-forming, thermoplastic behavior, regulatory-compliant |
| Benefits | Improved API stability, enhanced dissolution performance, scalable manufacturing compatibility |
| Regulatory Status | USP/NF, Ph. Eur., JP listed; DMF available |
| Storage Conditions | Store in original container at 15–30 °C, protect from moisture |
Contact With Us:
E-mail: wangxingqiang@ericwchem.com
Have a Questions? Call Us:
Add:
Building A1, Jiete Industrial Park, Huangpu District, Guangzhou City, Guangdong Province, China