Features Of Ashland Benecel 2208K K750 Hydroxypropyl Methylcellulose
High viscosity grade offering excellent thickening and suspension performance in aqueous systems.
Excellent thermal gelation profile with reversible gel formation above ~55–65 °C, enabling controlled release and texture stabilization.
Good compatibility with electrolytes and common formulation ingredients, including surfactants and preservatives.
Consistent batch-to-batch performance due to stringent Ashland manufacturing controls and purified cellulose feedstock.
Non-ionic nature ensures stability across broad pH range (3–11) without precipitation or charge-related incompatibility.
Typical Applications Of Ashland Benecel 2208K K750 Hydroxypropyl Methylcellulose
Pharmaceutical oral suspensions and controlled-release tablet matrices.
Architectural coatings requiring sag resistance, spatter resistance, and open-time extension.
Tile adhesives and cement-based mortars for improved workability and water retention.
Personal care gels and emulsions where thermal responsiveness and clarity are critical.
Food-grade stabilizers in dairy alternatives and plant-based beverages (subject to regional regulatory approval).
Specifications Of Ashland Benecel 2208K K750 Hydroxypropyl Methylcellulose
| Chemical Type | Hydroxypropyl methylcellulose (HPMC) |
| Product Form | White to off-white free-flowing powder |
| Appearance | Odorless, fine granular powder |
| Viscosity (2% aqueous solution at 20 °C) | 700–900 mPa·s (Brookfield RV, spindle #3, 12 rpm) |
| Methoxy Substitution (wt%) | 19.0–24.0% |
| Hydroxypropoxy Substitution (wt%) | 4.0–7.5% |
| pH (1% aqueous solution) | 5.0–8.0 |
| Moisture Content (max) | 5.0% w/w |
Ashland Benecel 2208K K750 Hydroxypropyl Methylcellulose – Frequently Asked Questions (FAQ)
Q1: What is the primary functional role of Benecel 2208K K750 in formulations?
A: Benecel 2208K K750 functions primarily as a water-soluble thickener and rheology modifier, providing pseudoplastic flow behavior, improved suspension stability, and enhanced film-forming capability in aqueous systems.
Q2: How does the K750 viscosity grade compare to other Benecel HPMC grades?
A: The 'K750' designation indicates a medium-to-high viscosity grade—measured as a 2% aqueous solution at 20°C—positioned between lower-viscosity grades like K100M and higher-viscosity variants such as K1500, offering balanced thickening efficiency and ease of hydration.
Q3: Is Benecel 2208K K750 suitable for use in pharmaceutical applications?
A: Yes—Benecel 2208K K750 is manufactured under pharmaceutical quality systems and complies with major pharmacopoeial requirements for HPMC, supporting its use in oral solid dosage forms, controlled-release matrices, and topical gels where viscosity control and gelation behavior are critical.
Q4: What are key handling considerations during incorporation into aqueous systems?
A: To avoid clumping, it is recommended to disperse Benecel 2208K K750 gradually into cold water under high shear; pre-blending with inert carriers (e.g., sugars or salts) or using a vortex mixer can improve wetting and accelerate full hydration.
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