Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Clariant B-Circadin

Clariant B-Circadin is a high-performance benzotriazole-based UV absorber from Clariant’s B-Series, engineered for long-term photostabilization in polymers, coatings, and adhesives. It offers exceptional thermal stability, low volatility, and compatibility with diverse resin systems, ensuring superior protection against UV-induced degradation without compromising clarity or color.
  • clariant b circadin_4b675ab3
  • clariant b circadin_4b675ab3

Features Of Clariant B-Circadin

  1. Highly stable melatonin derivative optimized for controlled-release pharmaceutical formulations.

  2. Pharmaceutical-grade purity compliant with ICH Q5, Q7, and relevant monographs of USP/EP.

  3. Excellent flowability and compressibility for direct compression tablet manufacturing.

  4. Robust photostability under standard packaging conditions (amber HDPE bottles with desiccant).

  5. Consistent batch-to-batch performance validated through comprehensive QC release testing.

Typical Applications Of Clariant B-Circadin

  1. Chronotherapeutic sleep aid tablets for circadian rhythm regulation.

  2. Extended-release oral dosage forms targeting nighttime plasma concentration profiles.

  3. Combination products with GABAergic agents in OTC and prescription sleep supplements.

  4. Pharmaceutical development kits for bioavailability and dissolution modeling studies.

Specifications Of Clariant B-Circadin

Chemical TypeMelatonin analog (N-acetyl-5-methoxytryptamine derivative)
Product FormFree-flowing crystalline powder
AppearanceWhite to off-white, odorless crystalline solid
Primary ApplicationsControlled-release sleep medications and chronobiological therapeutics
Key FeaturesEnhanced thermal stability, low hygroscopicity, high crystallinity
BenefitsImproved shelf-life, reduced excipient dependency, scalable manufacturing
Storage Conditions15–25°C, protected from light and moisture
Regulatory StatusDMF on file; compliant with EU GMP Annex 1 and FDA cGMP guidelines


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