Highly efficient silylating agent for rapid derivatization of hydroxyl, carboxyl, amino, and amide functional groups.
Low volatility and excellent thermal stability, enabling controlled reaction conditions in analytical and synthetic workflows.
Produces volatile trimethylsilyl (TMS) derivatives ideal for gas chromatography (GC) and GC-MS analysis.
Minimal side reactions and high derivatization yield, ensuring reproducible and accurate quantitative results.
Compatible with automated sample preparation systems and widely used in pharmaceutical and environmental testing laboratories.
Derivatization of polar analytes (e.g., steroids, fatty acids, sugars) prior to gas chromatographic analysis.
Sample preparation for residual solvent and impurity profiling in active pharmaceutical ingredients (APIs).
Stabilization of labile compounds during extraction and storage in environmental water and soil testing.
Enhancement of detection sensitivity and peak resolution in forensic toxicology screening protocols.
Functional group protection in fine chemical synthesis and peptide modification processes.
| Chemical Type | N,O-bis(trimethylsilyl)acetamide (BSA) |
| Product Form | Liquid |
| Appearance | Colorless to pale yellow clear liquid |
| Molecular Formula | C8H21NOSSi2 |
| Molecular Weight | 227.43 g/mol |
| Boiling Point | ~110–115 °C at 10 mbar |
| Density (20 °C) | 0.87–0.89 g/cm³ |
| Storage Condition | Store under inert atmosphere (N₂ or Ar) at 2–8 °C; protect from moisture |
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E-mail: wangxingqiang@ericwchem.com
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