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Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

H-HPC High Substituted Hydroxypropyl Cellulose

H-HPC High Substituted Hydroxypropyl Cellulose is a premium-grade, non-ionic cellulose ether from the H-HPC series—model H-HPC HS—featuring exceptionally high molar substitution (MS >2.0), outstanding solubility in cold water, superior film-forming ability, and enhanced thermal stability for demanding pharmaceutical and specialty applications.
  • h hpc high substituted hydroxypropyl cellulose_2af8c0cb
  • h hpc high substituted hydroxypropyl cellulose_2af8c0cb

Features Of H-HPC High Substituted Hydroxypropyl Cellulose

  1. High degree of substitution (DS > 2.5) ensures excellent water solubility across broad pH and ionic strength ranges.

  2. Superior thermal stability with gelation onset above 90 °C, enabling high-temperature processing compatibility.

  3. Low viscosity at high concentrations supports efficient pumping, mixing, and uniform film formation in coating applications.

  4. Non-ionic nature prevents interaction with charged APIs or excipients, enhancing formulation stability in pharmaceutical systems.

  5. USP/NF and EP compliant grade available, meeting stringent regulatory requirements for oral and topical dosage forms.

Typical Applications Of H-HPC High Substituted Hydroxypropyl Cellulose

  1. Sustained-release matrix tablets and hot-melt extrusion (HME) carriers in oral solid dosage forms.

  2. Viscosity modifier and stabilizer in ophthalmic solutions and gels requiring non-irritating, mucoadhesive performance.

  3. Binders and film formers in water-based industrial coatings and architectural paints.

  4. Thickening agent in personal care formulations including shampoos, conditioners, and hand sanitizers.

  5. Dispersing aid and protective colloid in pigment dispersions and ceramic slip casting processes.

Specifications Of H-HPC High Substituted Hydroxypropyl Cellulose

Chemical TypeNon-ionic cellulose ether derivative
Product FormWhite to off-white free-flowing powder
AppearanceOdorless, tasteless, fine granular powder
Primary ApplicationsPharmaceutical excipient, industrial thickener, functional binder
Key FeaturesHigh substitution, rapid cold-water dispersion, thermoreversible gelation
BenefitsEnhanced processability, robust formulation compatibility, regulatory acceptance
ComplianceMeets USP/NF, Ph. Eur., and JP monographs for HPC
Storage ConditionStore in cool, dry place; protect from moisture and direct sunlight


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