Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Eastman CAP-NF Cellulose Acetate Phthalate

Eastman CAP-NF is a high-purity cellulose acetate phthalate polymer from Eastman’s CAP series, designed for enteric coating and controlled-release pharmaceutical applications. It offers excellent film-forming ability, pH-dependent solubility (insoluble below pH 5.0), and regulatory compliance for oral solid dosage forms.
  • eastman cap nf cellulose acetate phthalate_66159aa5
  • eastman cap nf cellulose acetate phthalate_66159aa5

Features Of Eastman CAP-NF Cellulose Acetate Phthalate

  1. Enteric polymer with pH-dependent solubility—insoluble below pH 5.0 and soluble above pH 5.5.

  2. High purity grade formulated without residual solvents or plasticizers, meeting stringent pharmaceutical excipient requirements.

  3. Excellent film-forming capability for robust, pinhole-free coatings on tablets and pellets.

  4. Consistent batch-to-batch performance validated through rigorous quality control and USP/NF compliance testing.

  5. Thermally stable with low moisture uptake, supporting long-term storage stability of coated dosage forms.

Typical Applications Of Eastman CAP-NF Cellulose Acetate Phthalate

  1. Gastro-resistant tablet coatings to prevent drug release in the stomach and enable targeted intestinal delivery.

  2. Enteric protection for acid-labile active pharmaceutical ingredients (APIs) such as proton pump inhibitors and antibiotics.

  3. Functional film coating for modified-release multiparticulate systems including beads and granules.

  4. Excipient in oral solid dosage forms compliant with USP <85>, EP 2.6.13, and JP standards.

  5. Base polymer for hot-melt extrusion formulations requiring pH-responsive dissolution behavior.

Specifications Of Eastman CAP-NF Cellulose Acetate Phthalate

Chemical TypeCellulose acetate phthalate (CAP)
Product FormWhite to off-white free-flowing powder
AppearanceOdorless, fine particulate solid
Primary ApplicationsPharmaceutical enteric coating and controlled-release matrix
Key FeaturespH-dependent solubility, film-forming, non-toxic, regulatory-compliant
ComplianceMeets USP/NF, EP, and JP monographs for Cellulose Acetate Phthalate
Storage ConditionsStore in original sealed container at 15–25 °C, protected from moisture
Regulatory StatusGRAS for food contact applications; listed in FDA Inactive Ingredients Guide (oral tablets/capsules)


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