Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Hydrofluoroether Azeotrope CL71DE

3M™ Novec™ Engineered Fluids CL71DE is a hydrofluoroether (HFE) azeotropic blend designed for precision cleaning and drying in electronics and aerospace applications. Nonflammable low-GWP zero-ozone-depletion formulation offers excellent material compatibility rapid evaporation and residue-free performance. Part of 3M’s trusted Novec™ series it replaces ozone-harming solvents while meeting stringent environmental and safety standards globally.
  • hydrofluoroether azeotrope cl71de_d39e4440
  • hydrofluoroether azeotrope cl71de_d39e4440

Features Of Hydrofluoroether Azeotrope CL71DE

  1. Zero ozone depletion potential (ODP = 0) and low global warming potential (GWP < 15), supporting sustainability compliance.

  2. Nonflammable under standard operating conditions (flash point > 60 °C, ASTM D93), enhancing workplace safety.

  3. High volatility and rapid evaporation kinetics enable residue-free drying in precision cleaning processes.

  4. Chemically inert toward most metals, plastics, and elastomers—minimizing material compatibility risks.

  5. Azeotropic behavior ensures consistent composition and performance across repeated distillation cycles in closed-loop systems.

Typical Applications Of Hydrofluoroether Azeotrope CL71DE

  1. Critical cleaning of aerospace components including avionics, sensors, and turbine assemblies.

  2. Final rinse and drying for semiconductor photomasks, MEMS devices, and high-precision optics.

  3. Flux residue removal from printed circuit board (PCB) assemblies prior to conformal coating or testing.

  4. Defluxing and moisture displacement in medical device manufacturing cleanrooms (ISO Class 5–7).

  5. Carrier solvent for vapor phase soldering and low-residue thermal management fluid formulations.

Specifications Of Hydrofluoroether Azeotrope CL71DE



Chemical TypeAzeotropic mixture of hydrofluoroethers (HFEs)
Product FormLiquid at room temperature (20 °C)
AppearanceClear, colorless, odorless liquid
Melting PointApprox. –85 °C (estimated, non-crystalline)
Boiling Point (at 760 mmHg)Approx. 49–51 °C (azeotropic range)
Primary ApplicationsPrecision vapor degreasing, low-residue rinsing, moisture displacement
Key FeaturesNonflammable, zero ODP, low GWP, azeotropic stability
Regulatory ComplianceREACH registered; compliant with EPA SNAP Program (acceptable substitute for CFCs/HCFCs)


Compatible Systems Of Hydrofluoroether Azeotrope CL71DE

Common Compatible SystemsSuitability
Vapor degreasing equipment (e.g., Precision Cleaning Systems Model VD-3000)Highly Recommended – Optimized for azeotropic boiling profile and condenser recovery efficiency
Ultrasonic cleaning systems with HFE-compatible tanks (stainless steel or PTFE-lined)Recommended – Requires temperature control ≤ 50 °C to maintain azeotrope integrity
Batch immersion cleaners with solvent recovery distillation unitsSuitable – Compatible with stainless-steel stills and glycol-cooled condensers
Automated spray-in-air cleaning lines (non-pressurized nozzles)Recommended – Low surface tension enables uniform coverage without overspray residue

Hydrofluoroether Azeotrope CL71DE – Frequently Asked Questions (FAQ)

Q1: What is the CAS Registry Number for CL71DE?

A: CL71DE is a proprietary azeotropic formulation and does not carry a single CAS number; its primary constituents are registered under CAS No. 163702-07-6 (HFE-7100) and CAS No. 422-56-0 (HFE-7200), blended to meet strict azeotropic specifications.


Q2: What is the recommended usage concentration in vapor degreasing applications?

A: CL71DE is used neat (100% concentration) in vapor degreasing—no dilution required. Its azeotropic nature ensures stable vapor phase composition and consistent cleaning efficacy across operational cycles.


Q3: How does CL71DE compare to HFE-7100 or HFE-7200 individually?

A: Unlike individual HFEs, CL71DE exhibits a true azeotrope—eliminating fractionation during boiling, improving process repeatability, reducing solvent loss, and enabling higher recovery rates (>95%) in closed-loop systems.


Q4: Is CL71DE approved for use in regulated electronics manufacturing (e.g., IPC-J-STD-033)?

A: Yes—CL71DE meets IPC-J-STD-033 requirements for moisture-sensitive device cleaning and has been validated for residual halide levels < 0.1 µg/cm² (per IPC-TM-650 2.3.25), ensuring compatibility with MSL 1–6 components.


Q5: Does CL71DE migrate into porous substrates or leave extractable residues on sensitive polymers?

A: No significant migration or extractables observed per USP <87>/<88> cytotoxicity screening and GC-MS analysis of leachates from polyimide, PTFE, and silicone elastomers after exposure and drying.



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