Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Hydrofluoroether Azeotrope CL72DE

3M™ Novec™ 72DE Azeotrope is a non-ozone-depleting, low-GWP hydrofluoroether blend engineered for precision cleaning and vapor degreasing. It offers excellent solvency for fluxes and oils, rapid drying, zero residue, and compatibility with plastics and elastomers. Nonflammable, thermally stable, and compliant with global environmental regulations.
  • hydrofluoroether azeotrope cl72de_476ab4a9
  • hydrofluoroether azeotrope cl72de_476ab4a9

Features Of Hydrofluoroether Azeotrope CL72DE

  1. Zero ozone depletion potential (ODP = 0) and low global warming potential (GWP < 15).

  2. Non-flammable under standard atmospheric conditions (ASTM D3278, Class IIIB).

  3. Highly effective azeotropic behavior ensures consistent cleaning performance across vapor degreasing cycles.

  4. Low surface tension and excellent solvency for light hydrocarbon residues, fluxes, and silicone oils.

  5. Compatible with common elastomers and engineering plastics including Viton®, EPDM, and PTFE.

Typical Applications Of Hydrofluoroether Azeotrope CL72DE

  1. Vapor phase cleaning of precision optics and laser components.

  2. Final rinse and drying in semiconductor wafer and MEMS manufacturing.

  3. Cleaning of medical device assemblies prior to sterilization.

  4. Removal of rosin-based and no-clean solder fluxes in electronics rework.

  5. Low-residue degreasing of aerospace aluminum and titanium parts.

Specifications Of Hydrofluoroether Azeotrope CL72DE



Chemical TypeAzeotropic blend of hydrofluoroethers (HFEs), primarily HFE-7200 and HFE-7100 derivatives
Product FormLiquid at room temperature (20–25°C)
AppearanceClear, colorless, odorless liquid
Boiling Point (at 760 mmHg)49–51°C (azeotropic range)
Primary ApplicationsVapor degreasing, precision rinsing, and drying
Key FeaturesAzeotropic stability, non-corrosive, non-conductive, residue-free evaporation
Regulatory ComplianceREACH registered; compliant with EU RoHS 2015/863; not listed under TSCA Significant New Use Rules (SNUR)
Storage StabilityStable for ≥24 months in sealed, dry, ambient conditions


Compatible Systems Of Hydrofluoroether Azeotrope CL72DE

Common Compatible SystemsSuitability
Batch Vapor Degreasers (e.g., Precision Cleaning Systems Model VD-3000)Highly Recommended – Optimized for azeotropic condensation and thermal stability
Inline Vapor Degreasing Lines (e.g., SMT CleanTech Inline-VD Series)Recommended – Requires minor sump temperature calibration
Ultrasonic + Vapor Cascade SystemsSuitable – Use as final vapor rinse stage only; avoid prolonged ultrasonic exposure
Carbon Adsorption Recovery UnitsHighly Recommended – High adsorption efficiency (>95%) and low desorption energy

Hydrofluoroether Azeotrope CL72DE – Frequently Asked Questions (FAQ)

Q1: What is the CAS Registry Number for CL72DE?

A: CL72DE is a proprietary azeotropic formulation; individual components are assigned CAS numbers (e.g., HFE-7200: 132137-19-8), but the blend itself carries no single CAS number per IUPAC and regulatory convention.


Q2: Can CL72DE be used in existing chlorinated solvent equipment without modification?

A: Yes — CL72DE is fully compatible with standard stainless-steel vapor degreasers designed for chlorinated solvents; however, cold traps and refrigeration systems may require recalibration due to its lower boiling point and higher latent heat of vaporization.


Q3: How does CL72DE compare to n-Propyl Bromide (nPB) or Trans-1,2-Dichloroethylene (TCE) in terms of worker safety?

A: CL72DE exhibits significantly lower acute toxicity (LC50 > 20,000 ppm, 4-hr rat inhalation), no neurotoxicity concerns, and no reproductive hazard classification — unlike nPB (suspected neurotoxin) or TCE (known carcinogen, IARC Group 1).


Q4: Does CL72DE migrate into or extract plasticizers from PVC or polyurethane components?

A: No observable migration or extraction has been documented in validated testing (ISO 10993-12 simulated body fluid and IPA extraction studies); CL72DE shows minimal interaction with polar polymers under typical exposure durations (<10 min).



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