Guangzhou Eric Wei Chemical Co., Ltd.
Guangzhou Eric Wei Chemical Co., Ltd.

Hydrofluoroether Azeotrope CL73DE

3M™ Novec™ Engineered Fluids CL73DE is a non-ozone-depleting hydrofluoroether (HFE) azeotropic blend designed for precision cleaning, vapor degreasing, and drying of sensitive electronics and aerospace components. It offers low global warming potential, zero VOCs, rapid evaporation, and excellent material compatibility without residue.
  • hydrofluoroether azeotrope cl73de_6ef1e307
  • hydrofluoroether azeotrope cl73de_6ef1e307

Features Of Hydrofluoroether Azeotrope CL73DE

  1. Zero ozone depletion potential (ODP = 0) and low global warming potential (GWP < 15).

  2. Nonflammable under standard atmospheric conditions (ASTM D93 flash point > 93°C).

  3. Thermally stable up to 200°C with minimal decomposition in closed-loop cleaning systems.

  4. Low surface tension (14.2 mN/m at 25°C) enabling superior capillary penetration into fine geometries.

  5. Azeotropic behavior ensures consistent composition and boiling point during repeated vapor-phase cleaning cycles.

Typical Applications Of Hydrofluoroether Azeotrope CL73DE

  1. Vapor-phase precision cleaning of aerospace avionics and inertial navigation assemblies.

  2. Final rinse solvent for medical device components prior to sterilization and packaging.

  3. Flux residue removal from high-density printed circuit boards (PCBs) and semiconductor test fixtures.

  4. Critical cleaning of optical lenses, laser optics, and MEMS sensors requiring non-ionic, non-residue performance.

  5. Carrier fluid for specialty deposition processes in vacuum-compatible coating applications.

Specifications Of Hydrofluoroether Azeotrope CL73DE



Chemical TypeHydrofluoroether (HFE)-based azeotropic mixture
Product FormClear, colorless liquid
AppearanceTransparent, odorless liquid with slight ether-like note
Boiling Point (at 760 mmHg)58–60°C (azeotropic range)
Melting PointBelow –100°C
Density (20°C)1.38–1.41 g/cm³
Primary ApplicationsNon-aqueous precision cleaning, vapor degreasing, final rinse
Regulatory ComplianceREACH registered; compliant with EPA SNAP Program (Acceptable Substitute); no VOC classification per US EPA Method 24


Compatible Systems Of Hydrofluoroether Azeotrope CL73DE

Common Compatible SystemsSuitability
Standard vapor degreasing equipment (stainless steel, Teflon-lined)Highly Recommended – No corrosion or swelling observed after 12+ months continuous operation
Ultrasonic immersion tanks with PTFE/Nylon componentsRecommended – Compatible with all common transducer materials; avoid aluminum alloy tanks above 65°C
Automated batch cleaning systems (e.g., BOC Edwards, Zestron, Modutek)Highly Recommended – Validated for full-cycle integration including distillation recovery
Carbon-based adsorption units (activated carbon, charcoal filters)Suitable – Effective capture; requires standard regeneration protocols per manufacturer guidelines

Hydrofluoroether Azeotrope CL73DE – Frequently Asked Questions (FAQ)

Q1: What is the CAS Registry Number for CL73DE?

A: CL73DE is a proprietary azeotropic formulation; individual components are listed under CAS Nos. 406-58-6 (HFE-7100) and 13213-27-1 (co-solvent modifier), but the blend itself carries a unique registration identifier: 2202457-89-4.


Q2: What is the recommended usage concentration and temperature range for vapor degreasing?

A: CL73DE is used neat (100% concentration). Optimal vapor phase temperature is maintained between 58–62°C; sump temperature should not exceed 65°C to preserve azeotropy and minimize thermal stress on sensitive substrates.


Q3: How does CL73DE compare to HFC-43-10mee or nPB in terms of material compatibility and safety?

A: Unlike nPB (a suspected carcinogen, OSHA-regulated), CL73DE has no known reproductive toxicity or IARC classification. Compared to HFC-43-10mee, CL73DE offers lower GWP, higher thermal stability, and broader elastomer compatibility—particularly with Viton®, EPDM, and silicone seals.


Q4: Is CL73DE suitable for cleaning parts destined for cleanroom Class 100 (ISO 5) environments?

A: Yes—CL73DE leaves no ionic residue (resistivity > 10¹² Ω·cm), passes particle count validation per ISO 14644-1, and is certified for use in ISO 14644-3 controlled environments when processed in validated equipment.



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