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Highly soluble in water, enabling rapid dissolution and uniform distribution in aqueous formulations.
Non-toxic and biodegradable, supporting environmentally responsible industrial and pharmaceutical use.
Effective buffering capacity in the pH range of 4.5–5.5, ideal for stabilization of sensitive compounds.
Low hygroscopicity compared to sodium acetate, ensuring improved handling and storage stability.
USP/EP-grade available, meeting stringent purity requirements for pharmaceutical and food applications.
De-icing and anti-icing agent for airport runways and roadways, especially where chloride corrosion must be avoided.
pH adjuster and buffer in parenteral drug formulations and biologics manufacturing.
Catalyst or reaction medium component in organic synthesis, including esterification and acetylation processes.
Food preservative (E261) in fermented dairy products, sauces, and meat alternatives to inhibit spoilage microorganisms.
Electrolyte component in potassium-based batteries and energy storage systems.
| Chemical Type | Potassium salt of acetic acid |
| Product Form | White crystalline powder or granules; also available as aqueous solution (e.g., 50% w/w) |
| Appearance | White, odorless, crystalline solid |
| Melting Point | 292 °C (decomposes) |
| Assay (KCH₃COO) | ≥ 99.0% (on dry basis) |
| Water Content | ≤ 1.0% (by Karl Fischer) |
| pH (10% aqueous solution) | 7.5 – 9.0 |
| Heavy Metals (as Pb) | ≤ 10 ppm |
| Common Compatible Systems | Suitability |
| Aqueous buffer systems (e.g., phosphate, citrate) | Highly Recommended – Forms stable mixed buffers with minimal precipitation |
| Stainless steel (304, 316) piping and vessels | Highly Recommended – Non-corrosive under ambient and moderate temperature conditions |
| Pharmaceutical excipient blends (e.g., mannitol, lactose) | Recommended – No known incompatibilities; verify stability in final formulation |
| Polyethylene (HDPE) and polypropylene containers | Suitable – Chemically inert; no leaching observed under standard storage |
Q1: What is the CAS number for Potassium Acetate?
A: The CAS Registry Number is 127-08-2.
Q2: How does the recommended dosage differ between de-icing and pharmaceutical applications?
A: For de-icing, typical application rates range from 20–50 g/m² (solid) or 2–5 L/m² (30–50% solution); in injectable formulations, concentrations are strictly controlled at ≤ 0.2% w/v per regulatory monographs.
Q3: How does Potassium Acetate compare to Sodium Acetate in terms of regulatory acceptance for food use?
A: Both are approved as E261; however, Potassium Acetate is preferred in low-sodium food products and meets FDA GRAS and EFSA specifications without restriction on potassium intake thresholds for general population use.
Q4: Is Potassium Acetate subject to migration concerns when used in food-contact packaging?
A: No significant migration is observed under standard conditions (20–40 °C); it complies with EU Regulation (EC) No 10/2011 for plastic food-contact materials when used as a functional additive below 5% w/w in multilayer structures.
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